China’s One-Child Policy (1979–2015) limited rural families to two children and urban families to one child. This practice, which led to the abandonment of hundreds of thousands of female infants, is indirectly responsible for the separate placement of infant twins. The availability of this sample launched the first prospective study of these pairs. Participants include families and twins comprising 15 monozygotic (MZA) pairs and 7 dizygotic (DZA) pairs from countries throughout the world. The research program is described, and the initial wave of IQ scores for MZA and DZA twin pairs is examined in the first comprehensive report from this study. The twins’ mean age at participation was 9.41 years (SD = 6.36), and their ages ranged from 3.19 to 24.98 years. Informative contrasts with adopted-together Chinese twins and virtual twins (same-age unrelated individuals reared together) highlight shared genetic and environmental effects on intellectual development. Applied directions based on findings from these novel samples are described.