Prolonged stress has been associated with elevated levels of circulating proinflammatory cytokines. Cyclo-oxygenase-2 inhibitors such as celecoxib exert anti-inflammatory effects and may enhance the response to antidepressant drug treatment in patients with depressive disorders, but their effect on anxiety symptoms in patients with anxiety disorders is uncertain.

中文翻译：

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塞来昔布增强抗抑郁药或抗焦虑药治疗对焦虑症患者情感症状和炎症标志物的影响：探索性研究。

长期的压力与循环促炎细胞因子水平升高有关。塞来昔布等环加氧酶2抑制剂发挥抗炎作用，可能增强抑郁症患者对抗抑郁药物治疗的反应，但它们对焦虑症患者焦虑症状的影响尚不确定。