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Knowledge Representation for Multi-Scale Physiology Route Modeling
Frontiers in Neuroinformatics ( IF 3.5 ) Pub Date : 2021-01-06 , DOI: 10.3389/fninf.2021.560050
Natallia Kokash 1 , Bernard de Bono 2
Affiliation  

We present a framework for the topological and semantic assembly of multiscale physiology route maps. The framework, called ApiNATOMY, consists of a knowledge representation (KR) model and a set of knowledge management (KM) tools. Using examples of ApiNATOMY route maps, we present a KR format that is suitable for the analysis and visualization by KM tools. The conceptual KR model provides a simple method for physiology experts to capture process interactions among anatomical entities. In this paper, we outline the KR model, modeling format, and the KM procedures to translate concise abstraction-based specifications into fully instantiated models of physiology processes.

中文翻译:

多尺度生理学路径建模的知识表示

我们提出了一个多尺度生理学路线图的拓扑和语义组装框架。该框架名为 ApiNATOMY,由知识表示 (KR) 模型和一组知识管理 (KM) 工具组成。使用 ApiNATOMY 路线图的示例,我们提出了一种适用于 KM 工具分析和可视化的 KR 格式。概念 KR 模型为生理学专家提供了一种简单的方法来捕获解剖实体之间的过程相互作用。在本文中,我们概述了 KR 模型、建模格式和 KM 程序,以将简洁的基于抽象的规范转换为生理过程的完全实例化模型。
更新日期:2021-03-17
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