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Serum‐ and glucocorticoid‐inducible kinase 1 promotes insulin resistance in adipocytes via degradation of insulin receptor substrate 1
Diabetes/Metabolism Research and Reviews ( IF 8 ) Pub Date : 2021-03-16 , DOI: 10.1002/dmrr.3451
Min Zhang 1 , Huan Chen 2 , Meng-Si Liu 2 , Ke-Ying Zhu 2 , Yan Hao 2 , Da-Long Zhu 2 , Ping Li 2
Affiliation  

Accumulating evidence indicates that serum‐ and glucocorticoid‐inducible kinase 1 (SGK1) plays a role in the development of metabolic syndrome via a poorly understood mechanism. This study aimed to investigate the direct effect of SGK1 on insulin sensitivity in adipose tissue.

中文翻译:

血清和糖皮质激素诱导激酶 1 通过降解胰岛素受体底物 1 促进脂肪细胞的胰岛素抵抗

越来越多的证据表明,血清和糖皮质激素诱导激酶 1 (SGK1) 通过一种知之甚少的机制在代谢综合征的发展中发挥作用。本研究旨在研究 SGK1 对脂肪组织胰岛素敏感性的直接影响。
更新日期:2021-05-10
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