Background and Aims. Flexible endoscopic treatment plays an important role in the treatment of Zenker’s diverticulum (ZD). This study analyzes long-term symptom control and the rate of adverse events in treatment-naïve patients and patients with recurrence, using the stag beetle knife junior (sb knife jr). Methods. From August 2013 to May 2019, 100 patients with symptomatic ZD were treated with flexible endoscopy using the sb knife jr. Before treatment, as well as 1 and 6 months afterwards, symptoms were obtained by a nine-point questionnaire, with symptoms weighted from 0 to 4. Results. Overall, 126 interventions were performed. The median follow-up period was 41 months (range 7-74). For the three most frequent symptoms, regurgitation, dysphagia, and dry cough, a significant reduction of the mean score could be achieved, from 2.85/3.45/2.85 before the initial treatment to 0.56/1.09/0.98 6 months later. 17 patients were retreated because of recurrence. Out of these, 12 patients underwent a 2^nd, 4 patients a 3^rd, and 1 patient a 4^th session, respectively. The mean dysphagia score for successfully treated patients could be reduced from initially 2.34 to 0.49/0.33/0.67 after the 1^st/2^nd/3^rd session, the frequency of dysphagia from 3.45 to 0.92/1.00/1.33, and the score for regurgitations from 2.85 to 0.35/1.00/0.67. In first-line treatment, as well as in retreatment, no severe adverse event occurred. Conclusion. Patients with ZD can be treated safely and effectively with the sb knife jr. Retreatment leads to equal symptom relief as compared to a successful first-line treatment and is not associated with a higher rate of adverse events.

中文翻译：

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内镜治疗曾克憩室：初治和预治疗患者的可比治疗结果

背景和目的。柔性内镜治疗在Zenker憩室（ZD）的治疗中起着重要作用。这项研究使用锹形甲虫小刀（sb knife jr）对未接受过治疗的患者和复发患者的长期症状控制和不良事件的发生率进行了分析。方法。从2013年8月到2019年5月，使用sb刀jr对100例有症状ZD的患者进行了柔性内镜检查。治疗前，以及1和6个月之后，通过一个九点问卷获得症状，与从0到4的加权症状结果。总共进行了126次干预。中位随访期为41个月（范围7-74）。对于三种最常见的症状，即反流，吞咽困难和干咳，可以将平均得分显着降低，从初始治疗前的2.85 / 3.45 / 2.85降至6个月后的0.56 / 1.09 / 0.98。由于复发，有17例患者被治愈。这些中，12例患者接受了2^次，4例患者有3^次，1例患者有4^个会话，分别。在^第1/2 ^nd / 3 ^rd后，成功治疗的患者的吞咽困难平均评分可以从最初的2.34降低到0.49 / 0.33 / 0.67会议期间，吞咽困难的频率从3.45降至0.92 / 1.00 / 1.33，反流得分从2.85降至0.35 / 1.00 / 0.67。在一线治疗以及再治疗中，没有发生严重的不良事件。结论。ZD患者可以使用sb刀小刀安全有效地治疗。与成功的一线治疗相比，再治疗可带来相同的症状缓解，并且与更高的不良事件发生率无关。