Selenium nanoparticles (SeNPs) are reinforced safe forms of the essential micronutrient selenium (Se) which take a lead in countless biotechnological and biomedical applications. The phycosynthesis of SeNPs was successfully investigated using cell-free extract of the microalgae, Spirulina platensis. The phycosynthesized S. platensis -SeNPs ( Sp SeNPs) were characterized using several characterization techniques such as UV-Visible, transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and energy dispersive X-ray. They were effectually achieved using different concentration from sodium selenite (Na 2 SeO 3 ) (1, 5, and 10 mM) to give size means of 12.64, 8.61, and 5.93 nm, respectively, with spherical shapes and highly negative zeta potentialities. The infrared analyses revealed the involvement of many phycochemials in Sp SeNPs production. The antibacterial properties of Sp SeNPs were confirmed, qualitatively and quantitatively, against foodborne microorganisms ( Staphylococcus aureus and Salmonella typhimurium ); the antibacterial activity was correlated and increased with SeNPs’ size diminution. The scanning micrographs of S. typhimurium cells treated with Sp SeNPs indicated the severe action of nanoparticles to destroy bacterial cells in time-dependent manners. The innovative facile phycosynthesis of SeNPs using S. platensis is recommended to generate effectual bioactive agents to control hazardous bacterial species.

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螺旋藻提取物对光合作用硒纳米颗粒的强效抗菌作用

硒纳米颗粒（SeNPs）是必需的微量营养元素硒（Se）的增强安全形式，在无数生物技术和生物医学应用中处于领先地位。使用微藻螺旋藻的无细胞提取物成功研究了SeNPs的光合作用。使用几种表征技术，例如紫外可见光，透射电子显微镜，傅里叶变换红外光谱，X射线衍射和能量色散X射线对植物合成的链霉菌-SeNPs（Sp SeNPs）进行表征。使用与亚硒酸钠（Na 2 SeO 3）不同的浓度（1、5和10 mM）分别达到12.64、8.61和5.93 nm的尺寸平均值，具有球形形状和高度负的Zeta电位，可以有效地实现这些目标。红外分析显示Sp SeNPs生产中涉及许多生化试剂。Sp SeNPs的定性和定量分析证明其对食源性微生物（金黄色葡萄球菌和鼠伤寒沙门氏菌）具有抗菌作用。抗菌活性与SeNPs的大小减小相关，并随SeNPs大小的减小而增加。用Sp SeNPs处理的鼠伤寒沙门氏菌细胞的扫描显微照片表明，纳米颗粒以强烈的时间依赖性方式破坏细菌细胞。推荐使用S. platensis进行创新性的简便的SeNPs植物光合作用，以产生有效的生物活性剂来控制有害细菌。抵抗食源性微生物（金黄色葡萄球菌和鼠伤寒沙门氏菌）；抗菌活性与SeNPs的大小减小相关，并随SeNPs大小的减小而增加。用Sp SeNPs处理的鼠伤寒沙门氏菌细胞的扫描显微照片表明，纳米颗粒以强烈的时间依赖性方式破坏细菌细胞。推荐使用S. platensis进行创新性的简便的SeNPs植物光合作用，以产生有效的生物活性剂来控制有害细菌。抵抗食源性微生物（金黄色葡萄球菌和鼠伤寒沙门氏菌）；抗菌活性与SeNPs的大小减小相关，并随SeNPs大小的减小而增加。用Sp SeNPs处理的鼠伤寒沙门氏菌细胞的扫描显微照片表明，纳米颗粒以强烈的时间依赖性方式破坏细菌细胞。推荐使用S. platensis进行创新性的简便的SeNPs植物光合作用，以产生有效的生物活性剂来控制有害细菌。