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NUMERICAL COUPLING ANALYSIS OF THE INFLUENCE OF BLOOD FLOW ON THE MECHANICAL RESPONSE FOR LIVER
Journal of Mechanics in Medicine and Biology ( IF 0.8 ) Pub Date : 2021-03-12 , DOI: 10.1142/s0219519421500184
JING YANG 1, 2 , LIUQING YANG 1 , SHANHONG MA 1 , DEMING ZHAO 1 , TAO QIN 2, 3
Affiliation  

As an important basis for determining the state of the liver, the mechanical responses are associated with many factors, and belong to a complex coupling system. Liver tissue has significantly complicated vascular channels. The vascular diameter, vascular deflection angle and vascular depth are defined as the key characteristic parameters. The influences of these parameters on the mechanical responses were analyzed. On the basis of the real mechanical parameters, the coupled numerical model of blood vessel, blood flow and liver tissue was established. The corresponding mechanical responses are obtained by utilizing the different vascular parameters. The effects of vascular parameters on the differences among the mechanical response difference and high strain modulus were analyzed. It was found that the blood vessels in the central area could reduce the liver mechanical response. The inner diameter parameter had main influences on the regions where the stain was more than 0.1. The mechanical difference is greater with larger inner diameter. The influences of vascular depth are greatest when the vascular depth was in the intermediate value, which would increase the liver mechanical responses. With the increment of vascular deflection angle, the liver mechanical response would also increase, and exceed the mechanical response without blood vessels. The findings after analyzing the influence of vascular parameters will provide a basis for the quantitative studies on the influence of blood vessels.

中文翻译:

血流对肝脏机械反应影响的数值耦合分析

作为判断肝脏状态的重要依据,力学反应与多种因素相关,属于一个复杂的耦合系统。肝组织具有明显复杂的血管通道。血管直径、血管偏转角和血管深度被定义为关键特征参数。分析了这些参数对机械响应的影响。在真实力学参数的基础上,建立了血管、血流和肝组织的耦合数值模型。通过利用不同的血管参数获得相应的机械响应。分析了血管参数对机械响应差异和高应变模量差异的影响。发现中央区域的血管可以降低肝脏的机械反应。内径参数对污点大于0.1的区域有主要影响。内径越大,机械差异越大。当血管深度处于中间值时,血管深度的影响最大,这会增加肝脏的机械反应。随着血管偏转角的增加,肝脏的机械反应也会增加,并超过无血管时的机械反应。分析血管参数影响后的发现将为血管影响的定量研究提供依据。内径越大,机械差异越大。当血管深度处于中间值时,血管深度的影响最大,这会增加肝脏的机械反应。随着血管偏转角的增加,肝脏的机械反应也会增加,并超过无血管时的机械反应。分析血管参数影响后的发现将为血管影响的定量研究提供依据。内径越大,机械差异越大。当血管深度处于中间值时,血管深度的影响最大,这会增加肝脏的机械反应。随着血管偏转角的增加,肝脏的机械反应也会增加,并超过无血管时的机械反应。分析血管参数影响后的发现将为血管影响的定量研究提供依据。并超过没有血管的机械反应。分析血管参数影响后的发现将为血管影响的定量研究提供依据。并超过没有血管的机械反应。分析血管参数影响后的发现将为血管影响的定量研究提供依据。
更新日期:2021-03-12
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