There is emerging evidence that emphasizes RDW as an optimal prognostic biomarker for cardiovascular diseases (Rejuvenation Research: https://pubmed.ncbi.nlm.nih.gov/30572793/ https://pubmed.ncbi.nlm.nih.gov/30132390/). However, there is hardly any evidence of interventions that are capable of modifying RDW. Our aim was to investigate the association of RDW levels and the response to an individualized exercise program in hospitalized older adults. To our knowledge, this is the first study that specifically looks at the impact of an intervention in this parameter among very old hospitalized patients. We have failed to show any change, but we consider that this result is also important in order to continue with the research of the strong correlation of RDW and different biological pathways.

中文翻译：

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住院老年人多组分运动期间的红细胞分布宽度 (RDW) 轨迹：随机临床试验的二次分析

有新的证据强调 RDW 作为心血管疾病的最佳预后生物标志物（复兴研究：https://pubmed.ncbi.nlm.nih.gov/30572793/https://pubmed.ncbi.nlm.nih.gov/30132390 /)。然而，几乎没有任何证据表明干预措施能够改变 RDW。我们的目的是调查 RDW 水平与住院老年人对个性化锻炼计划的反应之间的关联。据我们所知，这是第一项专门研究干预对高龄住院患者这一参数的影响的研究。我们没有表现出任何变化，但我们认为这个结果对于继续研究 RDW 与不同生物途径的强相关性也很重要。