Successful navigation of the HIV care continuum is necessary to maintain viral suppression. We explored gender-stratified correlates of being virally unsuppressed in the Prevention for Positives (P4P) component of HPTN 065. The outcome of interest was unsuppressed viral load (> 40 copies/mL) among individuals already living with HIV. Correlates included medication adherence factors, social support and stigma. Logistic regression models were stratified by gender (N = 673). Men-specific correlates of being virally unsuppressed included opposite-sex partners, older age and HIV disclosure stigma. Women-specific correlates included time since diagnosis, and personal-level barriers to medication adherence. When more individuals knew about their HIV status, women had over twice the likelihood of being virally unsuppressed; no such association was seen among men. Additionally, higher levels of social support were not associated with viral suppression among women. Interventions should consider gender-specific approaches to engaging social support in de-stigmatization of HIV and promotion of medication adherence and subsequent viral suppression.

要保持病毒抑制，必须成功导航HIV护理连续体。我们研究了HPTN 065阳性预防（P4P）组件中病毒未抑制的按性别分层的相关因素。感兴趣的结果是已经感染HIV的患者的病毒载量未抑制（> 40拷贝/ mL）。相关因素包括药物依从性，社会支持和污名。Logistic回归模型按性别分层（N = 673）。男性不受病毒抑制的相关因素包括异性伴侣，年龄较大和艾滋病毒感染者的耻辱感。特定于女性的相关因素包括诊断以来的时间以及药物依从性的个人水平障碍。当更多的人知道自己的艾滋病毒感染状况时，妇女受到病毒抑制的可能性就会增加两倍以上。在男性中没有这种关联。另外，较高水平的社会支持与妇女中的病毒抑制无关。干预措施应考虑针对性别的方法，以使社会支持参与消除艾滋病毒的污名化并促进药物依从性和随后的病毒抑制。