Silk fibroin fiber is a unique biopolymer with high potential for medical applications. Dissolution and regeneration of fibroin using traditional solvents causes conformational transformations of the native fibroin structure and poor physicomechanical characteristics of materials prepared from it. The supramolecular structure can be regulated during precipitation. Herein, regeneration of fibroin using ionic liquids was investigated using IR spectroscopy and x-ray structure analysis. MeOH was shown to be the strongest precipitant for fibroin solutions in ionic liquids and could produce a supramolecular structure close to that of native fibroin. The fibroin precipitation conditions were mollified if alcohols with hydrocarbon radicals increasing in the order C₁-C₄ were used as precipitants.

丝素蛋白纤维是一种独特的生物聚合物，具有很高的医疗应用潜力。使用传统溶剂对丝蛋白的溶解和再生会导致天然丝蛋白结构的构象转变，以及由此制备的材料的物理机械性能较差。在沉淀过程中可以调节超分子的结构。在此，使用IR光谱和X射线结构分析研究了使用离子液体的丝蛋白的再生。甲醇被证明是离子液体中丝蛋白溶液的最强沉淀剂，可产生与天然丝蛋白接近的超分子结构。如果具有烃基的醇以C ₁ -C ₄的顺序增加，则丝素蛋白的沉淀条件将得到缓解。 被用作沉淀剂。