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Prior transfusion of umbilical cord mesenchymal stem cells can effectively alleviate symptoms of motion sickness in mice through interleukin 10 secretion.
World Journal of Stem Cells ( IF 4.1 ) Pub Date : 2021-3-13 , DOI: 10.4252/wjsc.v13.i2.177
Hua-Su Zhu , Dong Li , Cong Li , Jin-Xian Huang , Shan-Shan Chen , Lan-Bo Li , Qing Shi , Xiu-Li Ju

Motion sickness (MS) is a disease that occurs during unbalanced movement, characterized by gastrointestinal symptoms and autonomic nervous system activation. Current clinical treatments for MS are limited. Recent evidence indicates that the levels of pro-inflammatory cytokines increase during MS and are associated with an inner ear immune imbalance. In the present study, mesenchymal stem cells (MSCs) have been shown to exert strong immuno-suppressive effects.

中文翻译:

事先输注脐带间充质干细胞可通过白介素10分泌有效减轻小鼠的晕动病症状。

运动病(MS)是一种在运动不平衡期间发生的疾病,其特征是胃肠道症状和自主神经系统激活。MS的当前临床治疗是有限的。最近的证据表明,促炎性细胞因子的水平在MS期间增加,并且与内耳免疫失衡有关。在本研究中,间充质干细胞(MSCs)已显示出强大的免疫抑制作用。
更新日期:2021-03-16
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