The aim of this paper is to summarise and evaluate the empirical support for the association between anxiety and cardiovascular disease (CVD) and to address challenges related to method and study design. We review results from meta-analyses and more recent findings on the association of anxiety and the risk of CVD. Depression and anxiety are often listed as psychosocial risk markers of CVD, but the role of anxiety as a risk factor for CVD has not received the same evidential support as the effects of depression. Through a narrative review we identified six meta-analyses as well as 15 recent large studies of anxiety and CVD that we summarise. Some of the conflicting findings may be artefacts of study design or population the sample is drawn from. Researchers should take care to be population specific, measurement specific and outcome specific, and to control for comorbid depression.

本文的目的是总结和评估对焦虑与心血管疾病（CVD）之间关系的经验支持，并解决与方法和研究设计相关的挑战。我们回顾了荟萃分析的结果以及关于焦虑症与CVD风险之间关系的最新发现。抑郁和焦虑常被列为CVD的社会心理危险标志物，但焦虑作为CVD的危险因素的作用并未得到与抑郁症相同的证据支持。通过叙述性综述，我们确定了6项荟萃分析以及我们总结的15项关于焦虑和CVD的近期大型研究。一些相互矛盾的发现可能是研究设计的假象或样本来源。研究人员应注意特定人群，特定测量和特定结果，