The current study examines depression and pain as potential contributors to patient-provider discordance in the assessment of lupus disease activity. The study conducted a secondary analysis of data obtained from the Childhood Arthritis and Rheumatology Research Alliance registry, with N = 859 adolescent participants. Assessments of pain, disease activity, and antidepressant medication use were collected from the patient and provider. Results indicated that depression might be underdiagnosed in pediatric lupus patients. While psychotropic medication and pain scores were independently related to greater patient-provider discordance regarding health status, pain mediated this relationship. Implications for treatment outcomes are discussed.

当前的研究检查抑郁和疼痛可能是导致狼疮疾病活动性评估中患者与医务人员不一致的潜在原因。该研究对从儿童关节炎和风湿病研究联盟注册中心获得的数据进行了二次分析，其中N  = 859名青少年参与者。从患者和提供者那里收集疼痛，疾病活动和抗抑郁药物的使用情况评估。结果表明，小儿狼疮患者的抑郁症可能未得到充分诊断。虽然精神药物和疼痛评分与健康状况上患者与供应商之间更大的不一致性独立相关，但疼痛介导了这种关系。讨论了对治疗结果的影响。