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Computed Tomography Imaging Predictors of Intracerebral Hemorrhage Expansion
Current Neurology and Neuroscience Reports ( IF 5.6 ) Pub Date : 2021-03-12 , DOI: 10.1007/s11910-021-01108-z
Xin-Ni Lv , Lan Deng , Wen-Song Yang , Xiao Wei , Qi Li

Purpose of Review

Hematoma expansion (HE) is strongly associated with poor clinical outcome and is a compelling target for improving outcome after intracerebral hemorrhage (ICH). Non-contrast computed tomography (NCCT) is widely used in clinical practice due to its faster acquisition at the presence of acute stroke. Recently, imaging markers on NCCT are increasingly used for predicting HE. We comprehensively review the current evidence on HE prediction using NCCT and provide a summary for assessment of these markers in future research studies.

Recent Findings

Predictors of HE on NCCT have been described in reports of several studies. The proposed markers, including swirl sign, blend sign, black hole sign, island sign, satellite sign, and subarachnoid extension, were all significantly associated with HE and poor outcome in their small sample studies after ICH.

Summary

In summary, the optimal management of ICH remains a therapeutic dilemma. Therefore, using NCCT markers to select patients at high risk of HE is urgently needed. These markers may allow rapid identification and provide potential targets for anti-HE treatments in patients with acute ICH.



中文翻译:

脑出血扩大的计算机断层扫描成像预测因子

审查目的

血肿扩大(HE)与不良的临床预后密切相关,并且是改善脑出血(ICH)后预后的一个令人信服的目标。非对比计算机断层扫描(NCCT)由于在急性中风时可以更快地获取,因此在临床实践中被广泛使用。最近,NCCT上的成像标记越来越多地用于预测HE。我们全面审查了使用NCCT进行的HE预测的当前证据,并提供了评估这些标志物的摘要,以供将来研究之用。

最近的发现

几项研究的报告中已经描述了NCCT中HE的预测因子。拟议的标志物,包括旋流征,混合征,黑洞征,岛征,卫星征和蛛网膜下腔扩张,均与脑出血相关,并且在ICH后进行小样本研究时结果差。

概括

综上所述,ICH的最佳管理仍然是一个治疗难题。因此,迫切需要使用NCCT标记来选择高HE风险的患者。这些标记物可以快速鉴定并为急性ICH患者的抗HE治疗提供潜在的靶标。

更新日期:2021-03-12
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