ABSTRACT

We aimed to screen for depression among a sample of adolescents with type 1 Diabetes Mellitus (T1DM) and to determine the impact of obesity and poor diabetic control as potential risk factors.

One hundred adolescents with T1DM (aged between 14 and 18 years) were randomly selected and subjected to detailed history, physical examination, and laboratory investigations. BMI and Glycated Hemoglobin (HbA1c) were measured. The “PHQ-9“ questionnaire- Arabic version was used to screen for depression. We found that 51% of the sample was at moderate to severe risk for depression. There was a statistically significant association between the depression and older age and female gender. Depression severity was positively correlated with HbA1c, frequency of hospital admission, presence of diabetic complications and the degree of obesity. In this study, the best cut-off points that could predict depression in T1DM adolescent patients were: HbA1c of >10.1 or more, while the best cut-off point regarding BMI was found to be more than >22.3 Kg/m².

We can conclude adolescents with T1DM are at increased risk for depression especially females, with poor diabetic control and overweight problems.

摘要

我们旨在筛查1型糖尿病（T1DM）青少年的抑郁症，并确定肥胖和糖尿病控制不佳作为潜在危险因素的影响。

随机选择一百名患有T1DM的青少年（年龄在14至18岁之间），并接受详细的病史，体格检查和实验室检查。测量BMI和糖化血红蛋白（HbA1c）。“ PHQ-9”问卷-阿拉伯文版本用于筛查抑郁症。我们发现51％的样本处于中度到重度的抑郁风险。抑郁与老年人和女性之间存在统计学上的显着关联。抑郁严重程度与HbA1c，入院频率，糖尿病并发症的存在和肥胖程度呈正相关。在这项研究中，可以预测青少年T1DM抑郁症的最佳临界点是：HbA1c> 10.1或更高，而关于BMI的最佳临界点则大于> 22.3 Kg / m²。

我们可以得出结论，患有T1DM的青少年患抑郁症的风险增加，尤其是女性，其糖尿病控制不良和超重问题。