A comparative analysis of the secondary structure of blood serum proteins was carried out in patients with multiple myeloma, chronic lymphocytic leukemia and in healthy donors. The secondary structure of proteins in serum was determined using an infrared spectroscopy method. It was demonstrated that the proposed approach allows one to register a decrease in the portion of α-helical regions and an increase in the number of β-sheets in the blood serum samples of patients with multiple myeloma compared with healthy donors and patients with chronic lymphocytic leukemia.

中文翻译：

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肿瘤血液学疾病患者血清的红外光谱

对患有多发性骨髓瘤，慢性淋巴细胞性白血病和健康供体的患者进行了血清蛋白二级结构的比较分析。使用红外光谱法确定血清中蛋白质的二级结构。结果表明，与健康的供体和慢性淋巴细胞性肝炎患者相比，多发性骨髓瘤患者的血清样品中α-螺旋区域的减少和β-折叠片数量的增加是一种可以记录的方法。白血病。