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The characteristics of nuclear membrane fluctuations in stem cells
Journal of The Royal Society Interface ( IF 3.9 ) Pub Date : 2021-03-10 , DOI: 10.1098/rsif.2020.1010
Sedigheh Ghanbarzadeh Nodehi 1 , G V Shivashankar 2, 3 , Jacques Prost 4, 5 , Farshid Mohammad-Rafiee 1, 6
Affiliation  

We analyse the stem cell nucleus shape fluctuation spectrum obtained from optical confocal microscopy on an hour time scale with 10 s resolution. In particular, we investigate the angular and time dependencies of these fluctuations, define appropriate correlation functions that reveal the fundamentally out of equilibrium nature of the observed fluctuations as well as their global anisotropy. Langevin equations respecting the symmetry of the system allow us to model the damped oscillatory behaviour of the time correlations.



中文翻译:

干细胞核膜波动的特点

我们以 10 秒的分辨率分析从光学共聚焦显微镜获得的干细胞核形状波动光谱,时间尺度为 1 小时。特别是,我们研究了这些波动的角度和时间依赖性,定义了适当的相关函数,揭示了观察到的波动的基本失衡性质以及它们的全局各向异性。考虑系统对称性的朗之万方程允许我们对时间相关性的阻尼振荡行为进行建模。

更新日期:2021-03-10
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