Aim

To compare the efficacy and acceptability of internet-delivered exposure therapy for panic disorder, to multi-component internet-delivered cognitive behavioral therapy (iCBT) that included controlled breathing, cognitive restructuring and exposure.

Methods

Participants with panic disorder, with or without agoraphobia, were randomized to internet-delivered exposure therapy (n = 35) or iCBT (n = 34). Both programs were clinician guided, with six lessons delivered over eight weeks. Outcomes included panic disorder and agoraphobia symptom severity, as well as depression symptom severity, functional impairment and days out of role.

Results

Participants in both conditions displayed a large reduction in panic disorder symptom severity (ds >1.30) from pre- to post-treatment. Participants in both conditions displayed medium to large reduction in agoraphobia and depression symptom severity, functional impairment and days out of role. Effects were maintained at three- and six-month follow-up. There was no significant difference between the interventions in clinical outcomes, adherence or treatment satisfaction.

Conclusions

Internet-delivered exposure therapy appeared to be as acceptable and efficacious as more established iCBT, despite including less strategies. However, a fully powered replication is now needed to compare the two approaches.

中文翻译：

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互联网提供的暴露疗法与互联网提供的认知行为疗法治疗恐慌症：一项随机对照试验

目的

为了比较互联网提供的针对恐慌症的暴露疗法的功效和可接受性，与互联网提供的多成分认知行为疗法（iCBT）（包括控制呼吸，认知结构调整和暴露）进行比较。

方法

患有恐慌症，有或没有广场恐惧症的参与者被随机分配到互联网提供的暴露疗法（n = 35）或iCBT（n  = 34）。这两个程序都是在临床医生的指导下进行的，在八个星期内提供了六个课程。结果包括恐慌症和恐旷症症状严重程度，以及抑郁症症状严重程度，功能障碍和无用天数。

结果

从治疗前到治疗后，两种情况下的参与者均表现出惊恐症症状严重程度的大幅度降低（d s> 1.30）。在这两种情况下，参与者表现出的中性恐惧症和抑郁症状的严重程度，功能障碍和无用天数都有中等程度的降低。在三个月和六个月的随访中保持效果。干预措施在临床结局，依从性或治疗满意度方面无显着差异。

结论

尽管包括较少的策略，但互联网提供的暴露疗法似乎与更成熟的iCBT一样可接受和有效。但是，现在需要全功能复制来比较这两种方法。