Multi-effect distillation (MED) desalination system always faces the inevitable fouling problem, which leads to a decrease in fresh water production and restricts its long-term efficient operation. This study focuses on improving the system's operation benefits in the full cycle. Firstly, an asymptotic model for fouling accumulation is added to a MED-TVC model, which takes into account the influence of operating conditions on the fouling rate. Subsequently, the impact of fouling accumulation on the operating state of the system is analyzed in the whole cycle, indicating the decrease of operating benefits. Finally, the full cycle operation optimization method is applied for the purpose of reducing motive steam consumption as well as meeting fresh water demand using control vector parameterization strategy. The result shows a significant reduction in motive steam consumption while maintaining fresh water production capacity, which confirms that full cycle optimization has a considerable effect on dealing with fouling problem in MED desalination systems.

多效蒸馏（MED）脱盐系统始终面临不可避免的结垢问题，这将导致淡水产量下降并限制其长期有效运行。这项研究的重点是在整个周期内提高系统的运行效益。首先，将积垢的渐近模型添加到MED-TVC模型中，该模型考虑了运行条件对积垢率的影响。随后，在整个周期内分析结垢积累对系统运行状态的影响，表明运行效益的下降。最后，采用全循环运行优化方法以减少动力蒸汽消耗并使用控制矢量参数化策略满足淡水需求。