Squamous cell carcinoma of the anal canal remains rare, with metastatic disease even less commonly reported. We present a case of a patient with both a prior history of squamous cell carcinoma of the anal canal as well as breast cancer, who was without evidence of disease for 1 year. She was subsequently found to have FDG-avid mediastinal lymphadenopathy, initially assumed to be related to her more recent breast cancer. However, a biopsy confirmed recurrent anal cancer, with HPV infection. This represents a novel site of spread for anal cancer, one not yet reported in the literature.
Gastrointest Tumors

中文翻译：

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纵隔淋巴结转移的肛门癌

肛管鳞状细胞癌仍然很少见，转移性疾病报道较少。我们介绍了一例既有肛管鳞状细胞癌史又有乳腺癌史的患者，该患者一年没有疾病证据。随后发现她患有FDG-avid纵隔淋巴结病，最初被认为与她最近的乳腺癌有关。然而，活检证实了复发性肛门癌，并感染了HPV。这代表了一种新的肛门癌扩散位点，文献中尚未报道。
胃肠道肿瘤