Physics in Medicine & Biology ( IF 3.5 ) Pub Date : 2021-03-03 , DOI: 10.1088/1361-6560/abbd17 Conor K McGarry 1, 2 , Lesley J Grattan 1 , Aoife M Ivory 3 , Francesca Leek 3, 4 , Gary P Liney 5, 6, 7 , Yang Liu 8 , Piero Miloro 3 , Robba Rai 5, 6, 7 , Andrew P Robinson 3, 9, 10 , Albert J Shih 8 , Bajram Zeqiri 3 , Catharine H Clark 3, 11, 12
Tissue mimicking materials (TMMs), typically contained within phantoms, have been used for many decades in both imaging and therapeutic applications. This review investigates the specifications that are typically being used in development of the latest TMMs. The imaging modalities that have been investigated focus around CT, mammography, SPECT, PET, MRI and ultrasound. Therapeutic applications discussed within the review include radiotherapy, thermal therapy and surgical applications. A number of modalities were not reviewed including optical spectroscopy, optical imaging and planar x-rays. The emergence of image guided interventions and multimodality imaging have placed an increasing demand on the number of specifications on the latest TMMs. Material specification standards are available in some imaging areas such as ultrasound. It is recommended that this should be replicated for other imaging and therapeutic modalities. Materials used within phantoms have been reviewed for a series of imaging and therapeutic applications with the potential to become a testbed for cross-fertilization of materials across modalities. Deformation, texture, multimodality imaging and perfusion are common themes that are currently under development.
中文翻译:
用于成像和治疗体模的组织模拟材料:综述
组织模拟材料 (TMM) 通常包含在体模中,已在成像和治疗应用中使用了数十年。本次审查调查了通常用于开发最新 TMM 的规范。已研究的成像方式集中在 CT、乳房 X 光检查、SPECT、PET、MRI 和超声波。审查中讨论的治疗应用包括放射治疗、热治疗和手术应用。许多方式没有审查,包括光谱学、光学成像和平面 X 射线。图像引导干预和多模态成像的出现对最新 TMM 的规范数量提出了越来越多的要求。材料规格标准可用于某些成像领域,例如超声波。建议对其他成像和治疗方式进行复制。幻影中使用的材料已经过一系列成像和治疗应用的审查,有可能成为跨模式材料交叉受精的试验台。变形、纹理、多模态成像和灌注是目前正在开发的常见主题。