Objectives: Fecal blood testing is a noninvasive alternative to colonoscopy for colorectal cancer (CRC) screening and is preferred by a substantial proportion of individuals. However, participant-related determinants of the choice of screening method, particularly up-to-date screening status, remain less studied. We aimed to determine if up-to-date screening status was related to choosing a fecal blood test over colonoscopy. Setting: Participants in the population-based cross-sectional survey study Bus Santé in Geneva, Switzerland – aged 50–69 years. Design: Cross-sectional survey study using mailed questionnaires inquiring about CRC screening method of choice after providing information on advantages and disadvantages of both screening methods. We used multivariable logistic regression models to determine the association between up-to-date CRC screening status and choosing fecal blood testing. Key results: We included 1,227 participants. Thirty-eight percent of participants did not have up-to-date CRC screening. Overall, colonoscopy (54.9%) was preferred to fecal blood testing (45.1%) (p #x3c; 0.001) as screening method of choice. However, screening method choices differed between those with (65.6% colonoscopy and 34.4% fecal blood testing) and without up-to-date CRC screening (36.5% colonoscopy and 63.5% fecal blood testing). Not having up-to-date CRC screening was associated with a higher probability of choosing fecal blood testing as screening method (odds ratio = 2.6 [1.9; 3.7], p #x3c; 0.001) after adjustment for the aforementioned confounders. Conclusions: Not having up-to-date screening was independently associated with fecal blood testing as the preferred method for CRC screening. Proposing this method to this subpopulation, in a context of shared decision, could potentially increase screening uptake in settings where it is already high.
Gastrointest Tumors

中文翻译：

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筛查状态作为决定结直肠癌筛查方法选择的决定因素：基于人群的知情调查

目的：粪便血液检测是结肠镜检查（CRC）筛查的一种无创替代结肠镜检查方法，并且是相当一部分个人的首选。但是，关于筛选方法选择的参与者相关决定因素，尤其是最新的筛选状态，仍缺乏研究。我们旨在确定最新的筛查状态是否与通过结肠镜检查选择粪便血液检查有关。背景：参加基于人口的横断面调查研究的参与者在瑞士日内瓦，年龄在50-69岁之间。设计：在提供有关两种筛查方法的优缺点的信息后，使用邮寄问卷调查横断面研究，以选择哪种CRC筛查方法。我们使用多变量logistic回归模型来确定最新的CRC筛查状态与选择粪便血液检测之间的关联。关键结果：我们包括1,227名参与者。38％的参与者没有进行最新的CRC筛查。总体而言，结肠镜检查（54.9％）优于粪便血液检查（45.1％）（p＃x3c; 0.001）作为选择的筛选方法。但是，筛查方法的选择在有筛查（65.6％结肠镜检查和34.4％粪便血液检测）和未进行最新CRC筛查（36.5％结肠镜检查和63.5％粪便血液检测）之间有所不同。在对上述混杂因素进行调整后，未进行最新的CRC筛查与选择粪便血液检测作为筛查方法的可能性更高（几率= 2.6 [1.9; 3.7]，p＃x3c; 0.001）。结论：没有最新筛查与粪便血液检测独立相关，是进行CRC筛查的首选方法。在共同决策的情况下，将此方法建议给该子人群，可能会增加已经很高的环境中的筛查吸收率。
胃肠道肿瘤