Formate dehydrogenase (FDH) catalyzes the conversion of formate (HCOO⁻) into carbon dioxide (CO₂), coupled with the reduction of NAD⁺ to NADH. FDH involvement in the response against abiotic stress is well established whereas FDH role against pathogen attack is less known. Therefore, the in silico correlation analysis of the FDH transcript with a biotic stress dataset was performed, which highlighted correlation with genes involved in the response against pathogen attack. Next, a reduction in the expression of an FDH reporter construct in the hydathodes of Arabidopsis thaliana leaves infected with Xanthomonas campestris pv campestris (Xcc) was observed. We also observed an increased proliferation of Xcc in the hydathodes of an atfdh1-5 mutant during the early stages of infection, which further supports FDH involvement in an early defense response activated in the hydathodes upon Xcc infection, possibly through modulation of formate levels.

甲酸脱氢酶（FDH）催化甲酸（HCOO转化^- ）转换成二氧化碳（CO ₂），再加上NAD的还原⁺至NADH。FDH参与了针对非生物胁迫的响应，这一点已得到充分确立，而FDH对抗病原体攻击的作用则鲜为人知。因此，使用生物应激数据集对FDH转录本进行了计算机相关分析，从而突出显示了与涉及病原体攻击反应的基因之间的相关性。接着，在FDH报道构建体的表达的减少的排水器拟南芥感染叶野油菜黄单PV油菜（XCC） 被观测到。我们还观察到的增加的增殖XCC在的排水器atfdh1-5在感染的早期阶段，这进一步支持FDH参与在在所述排水器激活一个早期防御反应突变体XCC感染，可能通过甲酸盐水平的调节。