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Lead concentrations in breast milk of Moroccan nursing mothers and associated factors of exposure: CONTAMILK STUDY
Environmental Toxicology and Pharmacology ( IF 4.3 ) Pub Date : 2021-03-05 , DOI: 10.1016/j.etap.2021.103629
Abha Cherkani-Hassani 1 , Meriem Slaoui 2 , Imane Ghanname 3 , Brahim Mojemmi 4 , Rachid Eljaoudi 5 , Abdelilah Belhaj 6 , Brahim Kers 6 , Majda Flayou 6 , Nezha Mouane 7
Affiliation  

The aim of CONTAMILK study was to estimate levels of contamination of breast milk (BM) of Moroccan nursing mothers by some xenobiotics including, lead (Pb), to identify associated factors of exposure and to determine the daily intake of newborns. Lead concentrations were determined in 70 samples of colostrum by ICPMS and a structured questionnaire was filled during milk collection to report participants’ data. The median lead concentration was 908 μg/L (range 1.38–515,39 μg/L) and in 79 % of samples, levels were higher than the normal range reported by the World Health Organization (WHO) in BM (2−5 μg/L). Indeed, preterm delivery, frequency of use of cosmetic powders and lipsticks were significantly associated with the level of lead in BM. The estimated daily intake was greater than the tolerable daily intake (TDI) of the European food safety authority (0.5 μg/kg/day) for 39 babies and 6 babies according to the WHO (3.6 μg/kg/day).



中文翻译:

摩洛哥哺乳母亲母乳中的铅浓度及相关暴露因素:CONTAMILK 研究

CONTAMILK 研究的目的是估计摩洛哥哺乳母亲的母乳 (BM) 被一些异生素(包括铅 (Pb))污染的水平,以确定相关的暴露因素并确定新生儿的每日摄入量。通过 ICPMS 测定了 70 个初乳样品中的铅浓度,并在牛奶收集过程中填写了结构化问卷以报告参与者的数据。铅浓度中位数为 908 μg/L(范围 1.38–515,39 μg/L),并且在 79% 的样品中,铅浓度高于世界卫生组织 (WHO) 报告的正常范围(2-5 μg/L) /L)。事实上,早产、化妆粉和口红的使用频率与 BM 中的铅含量显着相关。

更新日期:2021-03-15
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