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Wavelength-specific optoacoustic-induced vibrations of the guinea pig tympanic membrane
Journal of Biomedical Optics ( IF 3.5 ) Pub Date : 2021-03-01 , DOI: 10.1117/1.jbo.26.3.038001
Larissa Heimann 1 , Christopher Carlein 2 , Katharina Sorg 1 , Rolf Diller 2 , Achim Langenbucher 3 , Bernhard Schick 1 , Gentiana Ioana Wenzel 1
Affiliation  

Significance: Optoacoustic-induced vibrations of the hearing organ can potentially be used for a hearing device. To increase the efficiency of such a hearing device, the conversion of the light energy into vibration energy within each type of irradiated tissue has to be optimized. Aim: To analyze the wavelength-dependency of optoacoustic-induced vibrations within the tympanic membrane (TM), and to define the most efficient and best-suited optical stimulation parameters for a novel auditory prosthesis. Approach: Single nanosecond laser pulses, continuously tunable in a range of visible to near-infrared, were used to excite the guinea pig TM. The induced vibrations of the hearing organ were recorded at the malleus using a laser Doppler vibrometer. Results: Our results indicate a strong wavelength-dependency of the vibration’s amplitude correlating with the superposition of the absorption spectra of the different specific tissue components. Conclusions: We investigated the spectrum of the vibrations of the hearing organ that were induced optoacoustically within a biological membrane embedded in air, in an animal model. First applications for these results can be envisioned for the optical stimulation of the peripheral hearing organ as well as for research purposes.

中文翻译:

豚鼠鼓膜的波长特定光声诱导振动

意义:听觉器官的光声引起的振动有可能用于听力设备。为了提高这种听力设备的效率,必须优化光能在每种受照射组织内向振动能的转换。目的:分析鼓膜 (TM) 内光声诱发振动的波长依赖性,并为新型听觉假体定义最有效和最适合的光刺激参数。方法:在可见光到近红外范围内连续可调的单个纳秒激光脉冲用于激发豚鼠 TM。使用激光多普勒振动计在锤骨处记录听力器官的诱发振动。结果:我们的结果表明,振动幅度的强波长依赖性与不同特定组织成分的吸收光谱的叠加相关。结论:我们在动物模型中研究了在嵌入空气中的生物膜内光声诱导的听觉器官的振动频谱。可以设想这些结果的首次应用可用于外周听觉器官的光学刺激以及研究目的。
更新日期:2021-03-05
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