Introduction: Cytomegalovirus (CMV) is the most common infection during pregnancy that poses the risk of congenital CMV infections (cCMV) worldwide. The aim of this study was to assess the seroprevalence and associated factors of CMV among pregnant women in Southern Ethiopia. Method: A cross-sectional study was conducted on consecutive women attending the delivery ward at Hawassa comprehensive and specialized hospital. Blood samples collected at the time of delivery were tested for CMV IgG and IgM using ELISA. Study participants responded to a questionnaire about obstetric history and socio-demographic characteristics. Data analysis was performed using SPSS version 20.0 software. Chi-square, bivariable and multivariable logistic regression were used to identify characteristics independently associated with the sero-status of CMV. Results: Seropositivity for CMV IgM antibodies was 8.2% (49/600) (95% CI: 6 -10.5%), whereas the CMV IgG was 88.6% (532/600), (95% CI: 89.5 - 94.0%). Seroprevalence was higher in women of older age, currently unmarried and having nursery schooled children. Moreover CMV seropositivity was significantly associated with any of detected curable STIs. Seroprevalence was not significantly related to previous adverse pregnancy outcome, gravidity, being a child day care occupant mother, and birth weight of the newborn. Conclusion: In the present study, we identified a high rate of CMV IgM seropositivity among pregnant women in southern Ethiopia. Given that there is no existing CMV diagnosis, special attention should be designed for pregnant women in parallel to the existing antenatal care facility. Besides, training health care professionals will support awareness conception among pregnant women concerning the sequels of CMV infection during pregnancy.

中文翻译：

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埃塞俄比亚南部产妇巨细胞病毒的血清阳性率及其相关因素

简介：巨细胞病毒（CMV）是怀孕期间最常见的感染，存在全球范围内先天性CMV感染（cCMV）的风险。这项研究的目的是评估埃塞俄比亚南部孕妇的CMV血清阳性率及其相关因素。方法：对在哈瓦萨综合专科医院分娩病房的连续妇女进行横断面研究。使用ELISA测试在分娩时收集的血液样品的CMV IgG和IgM。研究参与者回答了有关产科史和社会人口统计学特征的问卷。使用SPSS 20.0版软件进行数据分析。卡方检验，双变量和多变量logistic回归用于确定独立于CMV血清状况的特征。结果：CMV IgM抗体的血清阳性率为8.2％（49/600）（95％CI：6 -10.5％），而CMV IgG为88.6％（532/600），（95％CI：89.5-94.0％）。年龄较高，目前未婚并育有托儿所的妇女的血清阳性率较高。此外，CMV血清反应阳性与任何可检测到的可治愈性传播感染均显着相关。血清阳性率与先前的不良妊娠结局，妊娠率，作为儿童日托的母亲以及新生儿的出生体重没有显着相关。结论：在本研究中，我们在埃塞俄比亚南部的孕妇中发现了较高的CMV IgM血清阳性率。鉴于目前尚无CMV诊断，应与现有的产前保健设施同时对孕妇进行特别注意。除了，