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Numerical investigation of some reductions for the Gatenby-Gawlinski model
arXiv - CS - Numerical Analysis Pub Date : 2021-03-03 , DOI: arxiv-2103.02657 Corrado Mascia, Pierfrancesco Moschetta, Chiara Simeoni
arXiv - CS - Numerical Analysis Pub Date : 2021-03-03 , DOI: arxiv-2103.02657 Corrado Mascia, Pierfrancesco Moschetta, Chiara Simeoni
The Gatenby-Gawlinski model for cancer invasion is object of analysis in
order to investigate the mathematical framework behind the model working by
means of suitable reductions. We perform numerical simulations to study the
sharpness/smoothness of the traveling fronts starting from a brief overview
about the full model and proceed by examining the case of a two-equations-based
and one-equation-based reduction. We exploit a numerical strategy depending on
a finite volume approximation and employ a space-averaged wave speed estimate
to quantitatively approach the traveling waves phenomenon. Concerning the one
equation-based model, we propose a reduction framed within the degenerate
reaction-diffusion equations field, which proves to be effective in order to
qualitatively recover the typical trends arising from the Gatenby-Gawlinski
model. Finally, we carry out some numerical tests in a specific case where the
analytical solution is available.
中文翻译:
Gatenby-Gawlinski模型的一些归约化的数值研究
分析癌症的Gatenby-Gawlinski模型是分析的对象,目的是通过适当减少来研究模型工作背后的数学框架。我们从关于完整模型的简要概述开始进行数值模拟,以研究行进线的锋利度/平滑度,然后通过研究基于两方程式和基于一方程式的折减的情况进行研究。我们采用一种基于有限体积近似的数值策略,并采用空间平均波速估计量来定量地逼近行波现象。关于一个基于方程的模型,我们提出了一个在简并反应扩散方程领域内的框架,它被证明是有效的,以定性地恢复由Gatenby-Gawlinski模型引起的典型趋势。最后,
更新日期:2021-03-05
中文翻译:
Gatenby-Gawlinski模型的一些归约化的数值研究
分析癌症的Gatenby-Gawlinski模型是分析的对象,目的是通过适当减少来研究模型工作背后的数学框架。我们从关于完整模型的简要概述开始进行数值模拟,以研究行进线的锋利度/平滑度,然后通过研究基于两方程式和基于一方程式的折减的情况进行研究。我们采用一种基于有限体积近似的数值策略,并采用空间平均波速估计量来定量地逼近行波现象。关于一个基于方程的模型,我们提出了一个在简并反应扩散方程领域内的框架,它被证明是有效的,以定性地恢复由Gatenby-Gawlinski模型引起的典型趋势。最后,