Propranolol hydrochloride can be considered a persistent and bioaccumulative pharmaceutical in the environment. This drug and its by-products are potentially toxic and have adverse effects, since these compounds have been associated with endocrine-disrupting effects, reproductive deficiencies, embryo abnormalities and pericardial oedema. TiO₂–La 0.05%–carboxymethyl-β-cyclodextrin (CMCD) nanoparticles were successfully prepared by a simple two-step method, which consists of sonification and functionalization. The characterization analyses reveal that lanthanum is dispersed on the semiconductor surface, probably forming Ti–O–La bonds, which can induce oxygen vacancies and surface defects that effectively restrain the recombination of photogenerated electron/holes pairs. The efficiency of TiO₂–La 0.05%–CMCD samples in degradation of propranolol under UV-light irradiation is higher than that of pristine TiO₂ within 20 min reaction, probably due to complex formation between the β-blocker and the oligosaccharide, which allows us to propose a photocatalytic mechanism based on the formation of intermediates and competition of these compounds to the radicals and CMCD cavities.

盐酸普萘洛尔可以被认为是一种在环境中具有持久性和生物蓄积性的药物。这种药物及其副产品具有潜在的毒性并具有副作用，因为这些化合物与内分泌干扰作用、生殖缺陷、胚胎异常和心包水肿有关。TiO ₂ -La 0.05%-羧甲基-β-环糊精（CMCD）纳米粒子通过简单的两步法成功制备，包括超声处理和功能化。表征分析表明，镧分散在半导体表面，可能形成Ti-O-La键，可诱导氧空位和表面缺陷，有效抑制光生电子/空穴对的复合。TiO _2的效率–La 0.05%–CMCD 样品在紫外光照射下降解普萘洛尔的反应在 20 分钟内高于原始 TiO ₂，​​这可能是由于 β-阻断剂和寡糖之间形成了复合物，这使我们能够提出一种光催化基于中间体的形成和这些化合物与自由基和 CMCD 空腔竞争的机制。