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IDDRRA: A novel platform, based on Geant4-DNA to quantify DNA damage by ionizing radiation
Medical Physics ( IF 3.8 ) Pub Date : 2021-03-03 , DOI: 10.1002/mp.14817
Konstantinos P. Chatzipapas 1 , Panagiotis Papadimitroulas 2 , George Loudos 2 , Niko Papanikolaou 3 , George C. Kagadis 1
Affiliation  

This study proposes a novel computational platform that we refer to as IDDRRA (DNA Damage Response to Ionizing RAdiation), which uses Monte Carlo (MC) simulations to score radiation induced DNA damage. MC simulations provide results of high accuracy on the interaction of radiation with matter while scoring the energy deposition based on state-of-the-art physics and chemistry models and probabilistic methods.

中文翻译:

IDDRRA:基于Geant4-DNA的新型平台,可通过电离辐射定量DNA损伤

这项研究提出了一种新的计算平台,我们将其称为IDDRRA(对电离辐射的DNA损伤响应),它使用蒙特卡罗(MC)模拟对辐射诱导的DNA损伤进行评分。MC模拟基于最新的物理和化学模型以及概率方法,在对辐射与物质的相互作用提供高精度的同时对能量沉积进行评分。
更新日期:2021-03-03
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