This case series describes acute corneal hydrops in three young horses. Due to similarities in the clinical appearance and progression of the disease with that which is reported in humans and cats with acute corneal hydrops, traumatic Descemet’s membrane rupture was suspected to be the underlying aetiology in these equine cases. The horses presented with acute severe corneal oedema with intrastromal bullae formation and anterior bulging of the corneal contour. Focal posterior corneal changes were also seen in two of three cases. Mild anterior uveitis was also present. Other causes of corneal oedema (e.g. glaucoma) were ruled out based on presentation and clinical examination. Treatment approaches were medical and included various combinations of prophylactic topical antimicrobial therapy in case of secondary corneal ulceration, anti-inflammatory therapy for uveitis, targeted oedema therapy with topical hypertonic saline and corneal cross-linking, and placement of a temporary partial tarsorrhaphy for corneal tamponade. The outcome was excellent in all cases, with rapid resolution of the ocular changes. Acute corneal hydrops of presumed traumatic Descemet’s membrane rupture origin should be considered in cases of young horses presenting with acute corneal oedema. However, further studies are warranted to better characterise the disease and to try to confirm the suspected aetiology.

中文翻译：

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推测为外伤性急性角膜积水：一个不受控制的病例系列（三匹马）

本病例系列描述了三匹小马的急性角膜积水。由于该疾病的临床表现和进展与在患有急性角膜积水的人和猫中所报道的相似，因此怀疑外伤性后丝氏膜破裂是这些马病例的潜在病因。这些马表现出急性严重的角膜水肿，伴有基质内大疱形成和角膜轮廓前部凸出。在三个病例中的两个中也观察到局部后角膜变化。还存在轻度前葡萄膜炎。根据表现和临床检查排除了角膜水肿的其他原因（例如青光眼）。治疗方法是医学的，包括在继发性角膜溃疡的情况下预防性局部抗菌治疗的各种组合，葡萄膜炎的抗炎治疗，局部高渗盐水和角膜交联的靶向水肿治疗，以及为角膜填塞放置临时部分睑板炎。所有病例的结果都非常好，眼部变化得到快速解决。在出现急性角膜水肿的年轻马的情况下，应考虑推测为外伤性 Descemet 膜破裂起源的急性角膜水肿。然而，需要进一步研究以更好地表征该疾病并尝试确认可疑的病因。在出现急性角膜水肿的年轻马的情况下，应考虑推测为外伤性 Descemet 膜破裂起源的急性角膜水肿。然而，需要进一步研究以更好地表征该疾病并尝试确认可疑的病因。在出现急性角膜水肿的年轻马的情况下，应考虑推测为外伤性 Descemet 膜破裂起源的急性角膜水肿。然而，需要进一步研究以更好地表征该疾病并尝试确认可疑的病因。