A 15-year-old captive female Urutu snake (Bothrops alternatus) was presented with anorexia, apathy, dehydration, pale mucous membranes and marked enlargement of the caudal third of the coelomic cavity. Radiographs and ultrasonography were suggestive of faecal impaction or neoplasia. Post-mortem findings consisted of solid faecal impaction of the intestines, secondary to obstruction caused by a rectal tumour. Cytological examination of impression smears of the tumour revealed polygonal to round neoplastic cells arranged in clusters in an abundant extracellular mucinous matrix. Histologically, there was transmural growth of neoplastic epithelial cells arranged in small nests or individually and immersed in abundant extracellular mucin lakes. The neoplastic cells were immunopositive for cytokeratin. Clinical and pathological aspects indicated a diagnosis of mucinous rectal adenocarcinoma.

一只 15 岁的圈养雌性乌鲁图蛇 ( Bothrops alternatus) 表现为厌食、冷漠、脱水、粘膜苍白和体腔尾部三分之一明显增大。X光片和超声检查提示粪便嵌塞或瘤形成。尸检结果包括肠道固体粪便嵌塞，继发于直肠肿瘤引起的梗阻。肿瘤印模涂片的细胞学检查显示多边形至圆形的肿瘤细胞成簇排列在丰富的细胞外粘液基质中。组织学上，肿瘤上皮细胞呈透壁生长，呈小巢状或单个排列，并浸入丰富的细胞外粘蛋白湖中。肿瘤细胞对细胞角蛋白呈免疫阳性。临床和病理学方面表明诊断为粘液性直肠腺癌。