Background: The aim of this study was to examine the impact of education, coronavirus disease 2019 (COVID-19), and risk factors on the quality of life in patients with type 2 diabetes. Methods: A prospective study was conducted in three phases: before education, after education, and in the period of pandemic coronavirus disease 2019 (COVID-19). The subjects were diabetics on oral therapy. To determine the quality of life index, a standardized Ferrans and Powers survey questionnaire was used. Results: A total of 205 participants took part in the study, of which 111 (54.1%) were men and 94 (46%) women. Participants were enrolled in the study between January 2019 and September 2020. Glycated hemoglobin values were significantly higher before education compared to post-education and at the time of COVID-19 (Friedman test, p = 0.002), and body mass index was significantly lower after education compared to values before education (Friedman test, p = 0.008). The quality of life was significantly lower in all domains in the COVID-19 period (Friedman test, p < 0.001). Conclusions: A significant predictor of worse assessment of overall quality of life was male gender and rural place of residence. Disease duration of up to 5 years was a significant predictor of worse assessment in the psychological/spiritual domain, while being married was a predictor of better assessment of the quality of life in the family domain. The education of diabetics brought an increase in the health and quality of life while the coronavirus disease pandemic had negative consequences on the same parameters. We consider it necessary to systematically educate diabetics about the comorbidity of COVID-19.

中文翻译：

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教育，COVID-19和危险因素对2型糖尿病患者生活质量的影响

背景：本研究的目的是检验教育程度，2019年冠状病毒病（COVID-19）和危险因素对2型糖尿病患者生活质量的影响。方法：前瞻性研究分三个阶段进行：教育前，教育后和大流行性冠状病毒病2019（COVID-19）期间。受试者是口服治疗的糖尿病患者。为了确定生活质量指数，使用了标准的Ferrans and Powers调查问卷。结果：共有205名参与者参加了研究，其中111名（54.1％）是男性，而94名（46％）是女性。参与者于2019年1月至2020年9月参加了该研究。与教育后相比和COVID-19时，糖化血红蛋白值显着高于教育前（弗里德曼检验，p= 0.002），并且受教育后的体重指数明显低于受教育前的数值（Friedman检验，p = 0.008）。在COVID-19期间，所有领域的生活质量均显着降低（Friedman检验，p<0.001）。结论：总体生活质量较差评估的一个重要预测因素是男性和农村居住地。长达5年的疾病持续时间是在心理/精神方面较差评估的重要预测指标，而结婚是对家庭方面生活质量较优评估的预测指标。糖尿病患者的教育提高了人们的健康和生活质量，而冠状病毒疾病大流行对相同参数产生了负面影响。我们认为有必要对糖尿病患者进行COVID-19合并症的系统教育。