The balance between self-renewal and differentiation of intestinal stem cells is essential for intestinal epithelial homeostasis, which can be regulated by dietary cues. Recent evidences indicate that metabolic pathways sense changes in nutritional status to control stem cell fate, which may provide new clues for the prevention of intestinal diseases.

中文翻译：

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肠道干细胞稳态的代谢调节

肠道干细胞的自我更新和分化之间的平衡对于肠道上皮稳态至关重要，这可以通过饮食线索进行调节。最近的证据表明，代谢途径感知营养状态的变化以控制干细胞的命运，这可能为预防肠道疾病提供新的线索。