As a medicinal and edible plant, Chrysanthemum morifolium cv. "Hangju" has economic value and is widely used as a Chinese herbal medicine and tea. However, the metabolomic difference between "Hangju" flowers with white and yellow petals is unclear. In this study, Chrysanthemum variety ZXYJ with white petals and its bud mutation strain JJYH with yellow petals were used as research materials. A preliminary study found that the relative content of total flavonoids in JJYH was 45.4% higher than that in ZXYJ. Combined transcriptomic and metabolomic analysis revealed that the phenylpropanoid biosynthetic pathway and the phenylalanine metabolic pathway had the highest degree of differentially expressed genes and significantly changed metabolites enrichment, respectively. The redirection of metabolic flux may contribute to increased accumulation of total flavonoid levels in JJYH, which may begin as early as phenylalanine metabolism. The results of this research provide a scientific basis for the development of products related to different colored medicinal chrysanthemums and references for the breeding of new varieties and the biosynthesis of phenylpropanoids.

菊花作为药用和食用植物简历。“杭菊”具有经济价值，被广泛用作中草药和茶。然而，尚不清楚带有白色和黄色花瓣的“ Hangju”花之间的代谢组学差异。本研究以白花瓣菊花品种ZXYJ及其黄色花瓣芽突变株JJYH为研究材料。初步研究发现，中药饮片中总黄酮的相对含量比中药饮片中的总黄酮含量高45.4％。转录组和代谢组学分析相结合显示，苯丙烷生物合成途径和苯丙氨酸代谢途径分别具有最高程度的差异表达基因和显着改变的代谢产物富集。代谢通量的重定向可能有助于JJYH中总黄酮水平的积累，它可能早于苯丙氨酸代谢开始。本研究结果为开发与不同颜色的菊花有关的产品提供了科学依据，并为新品种的选育和苯丙烷类化合物的生物合成提供了参考。