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Regulation of Ribosomal Protein Synthesis in Prokaryotes
Molecular Biology ( IF 1.2 ) Pub Date : 2021-02-26 , DOI: 10.1134/s0026893321010118
A. O. Mikhaylina , E. Y. Nikonova , O. S. Kostareva , S. V. Tishchenko

Abstract

Protein synthesis on ribosomes is considered the main process in cell life. Regulation of ribosomal protein gene expression plays an important role in the balanced synthesis of proteins and RNA in ribosomal biogenesis. This review is focused on some features of autoregulation of ribosomal protein synthesis in prokaryotes. Inhibition of the synthesis of ribosomal proteins encoded by 12 operons by mechanisms of competition , “entrapment”, and retroregulation are discussed. Examples of regulation of protein synthesis by individual ribosomal proteins and their complexes are presented.



中文翻译:

原核生物中核糖体蛋白合成的调控

摘要

核糖体上的蛋白质合成被认为是细胞生命的主要过程。核糖体蛋白基因表达的调节在核糖体生物发生中蛋白质和RNA的平衡合成中起着重要作用。这篇综述集中于原核生物中核糖体蛋白合成的自动调节的一些特征。讨论了通过竞争,“诱捕”和逆向调节机制抑制由12个操纵子编码的核糖体蛋白的合成。给出了由单个核糖体蛋白及其复合物调节蛋白合成的例子。

更新日期:2021-02-26
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