Natural Product Communications ( IF 1.8 ) Pub Date : 2021-02-24 , DOI: 10.1177/1934578x21992261 Tsukasa Iwashina 1 , Rinchen Yangzom 2 , Hari Prasad Devkota 3 , Takayuki Mizuno 1
Five flavonol O-glycosides and 4 C-glycosylflavones were isolated from the flowers of the Himalayan Megacodon stylophorus (Gentianaceae). They were characterized as quercetin 3-O-glucoside (1), quercetin 3-O-rutinoside (2), kaempferol 3-O-glucoside (3), isorhamnetin 3-O-glucoside (4) and kaempferol 3,7-di-O-glucoside (5) (flavonols), and isovitexin (6), isoorientin (7), isovitexin X″-O-arabinoside (8) and isovitexin 4′-O-glucoside (9) (C-glycosylflavones) by ultraviolet, liquid chromatography-mass spectrometry, acid hydrolysis, nuclear magnetic resonance, and/or high-performance liquid chromatography and thin-layer chromatography comparisons with authentic samples. On the other hand, 5 C-glycosylflavones were isolated from the leaves and identified as 6, 7, 9, vitexin (10), and orientin (11). Although many C-glycosylflavones and xanthones have been reported from Gentianaceae species, flavonols are minor occurrence in the family. Flavonoids were reported from the Megacodon species for the first time.
中文翻译:
喜马拉雅巨齿花(龙胆科)的花和叶中的类黄酮
从喜马拉雅西番莲(龙胆科)的花中分离出五个黄酮O-糖苷和四个C-糖基黄酮。它们的特征是槲皮素3- O-葡萄糖苷(1),槲皮素3- O-芸苔苷(2),山emp酚3- O-葡萄糖苷(3),异鼠李素3- O-葡萄糖苷(4)和山ka酚3,7-di - ø葡糖苷(5)(黄酮醇),异牡荆苷和(6),异荭草素(7),异牡荆苷X“ - ö -arabinoside(8),液相色谱-质谱,酸水解,核磁共振和/或高效液相色谱和薄层色谱与真品样品的比较)和异维毒素4'- O-葡萄糖苷(9)(C-糖基黄酮) 。在另一方面,5个Ç -glycosylflavones从叶子分离并鉴定了6,7,9,牡荆素(10),和荭(11)。尽管从龙胆科物种中已经报道了许多C-糖基黄酮和黄嘌呤,但是黄酮醇在该科中很少发生。黄酮类化合物从首次发现巨齿鲨物种。