Purpose of Review

The use of cannabis for the treatment of migraine has become an area of interest with the legalization of medical cannabis in the USA. Understanding the mechanisms of cannabinoids, available studies, and best clinical recommendations is crucial for headache providers to best serve patients.

Recent Findings

Patients utilizing medical cannabis for migraine have reported improvement in migraine profile and common comorbidities. Reduction in prescription medication is also common, especially opioids. Side effects exist, with the majority being mild. Not enough data is available for specific dose recommendations, but THC and CBD appear to mediate these observed effects.

Summary

The purpose of this article is twofold: review the limited research surrounding cannabis for migraine disease and reflect on clinical management experiences to provide recommendations that best capture the potential use of cannabis for migraine.

中文翻译：

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大麻和偏头痛：很复杂

审查目的

随着美国医用大麻合法化，使用大麻治疗偏头痛已成为一个令人感兴趣的领域。了解大麻素的机制、现有研究和最佳临床建议对于头痛提供者为患者提供最佳服务至关重要。

最近的发现

使用医用大麻治疗偏头痛的患者报告偏头痛症状和常见合并症有所改善。减少处方药也很常见，尤其是阿片类药物。存在副作用，大多数是轻微的。没有足够的数据可用于特定的剂量建议，但 THC 和 CBD 似乎可以调节这些观察到的影响。

概括

本文的目的有两个：回顾围绕大麻治疗偏头痛疾病的有限研究，并反思临床管理经验，以提供最能捕捉大麻治疗偏头痛潜在用途的建议。