ABSTRACT

With the development of today’s technology, the electromagnetic radiation spread by mobile phones and base stations is also rapidly increasing, and this causes serious concerns about the environment and human health. The Drosophila model organism is widely used in genetic toxicology studies because its genome is highly similar to the genes identified in human diseases. In this study, the genotoxic effects of radiofrequency electromagnetic radiation were evaluated by the wing Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster at 900 MHz, 1800 MHz, and 2100 MHz. The SMART method is based on the observation of genetic changes occurring in the trichomes of the Drosophila wings appearing as mutant clones under the microscope. Throughout the study, total clone parameters were evaluated by exposing the Drosophila larvae to electromagnetic fields for two, four, and six hours per day for two days. As a result of the study, it was observed that the number of mutant clones was statistically increased according to the negative control group in all applications except for the six-hour application at 1800 MHz.

摘要

随着当今科技的发展，手机和基站传播的电磁辐射也在迅速增加，这引起了人们对环境和人类健康的严重关注。所述果蝇模型有机体被广泛用于遗传毒性研究，因为其基因组中是高度相似的人类疾病中鉴定的基因。在这项研究中，通过900 MHz、1800 MHz 和 2100 MHz 的黑腹果蝇的翼体细胞突变和重组测试 (SMART) 评估了射频电磁辐射的基因毒性作用。SMART 方法基于对果蝇毛状体中发生的遗传变化的观察翅膀在显微镜下表现为突变克隆。在整个研究过程中，通过将果蝇幼虫每天暴露于电磁场 2、4 和 6 小时，持续两天来评估总克隆参数。作为研究的结果，观察到突变克隆的数量根据阴性对照组在所有应用中统计增加，除了在 1800 MHz 下应用 6 小时。