当前位置: X-MOL 学术Biomed. Opt. Express › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Motion-compensated noninvasive periodontal health monitoring using handheld and motor-based photoacoustic-ultrasound imaging systems
Biomedical Optics Express ( IF 3.4 ) Pub Date : 2021-02-23 , DOI: 10.1364/boe.417345
Moein Mozaffarzadeh 1, 2 , Colman Moore 2, 3 , Erfan Barzegar Golmoghani 2, 4 , Yash Mantri 5 , Ali Hariri 3 , Alec Jorns 3 , Lei Fu 3 , Martin D Verweij 1, 6 , Mahdi Orooji 4 , Nico de Jong 1, 6 , Jesse V Jokerst 3, 7, 8
Affiliation  

Simultaneous visualization of the teeth and periodontium is of significant clinical interest for image-based monitoring of periodontal health. We recently reported the application of a dual-modality photoacoustic-ultrasound (PA-US) imaging system for resolving periodontal anatomy and periodontal pocket depths in humans. This work utilized a linear array transducer attached to a stepper motor to generate 3D images via maximum intensity projection. This prior work also used a medical head immobilizer to reduce artifacts during volume rendering caused by motion from the subject (e.g., breathing, minor head movements). However, this solution does not completely eliminate motion artifacts while also complicating the imaging procedure and causing patient discomfort. To address this issue, we report the implementation of an image registration technique to correctly align B-mode PA-US images and generate artifact-free 2D cross-sections. Application of the deshaking technique to PA phantoms revealed 80% similarity to the ground truth when shaking was intentionally applied during stepper motor scans. Images from handheld sweeps could also be deshaken using an LED PA-US scanner. In ex vivo porcine mandibles, pigmentation of the enamel was well-estimated within 0.1 mm error. The pocket depth measured in a healthy human subject was also in good agreement with our prior study. This report demonstrates that a modality-independent registration technique can be applied to clinically relevant PA-US scans of the periodontium to reduce operator burden of skill and subject discomfort while showing potential for handheld clinical periodontal imaging.

中文翻译:

使用手持和基于电机的光声超声成像系统进行运动补偿的无创牙周健康监测

牙齿和牙周组织的同时可视化对于基于图像的牙周健康监测具有重要的临床意义。我们最近报道了双模态光声超声 (PA-US) 成像系统在解决人类牙周解剖和牙周袋深度方面的应用。这项工作利用连接到步进电机的线性阵列换能器通过最大强度投影生成 3D 图像。这项先前的工作还使用医用头部固定器来减少由主体运动(例如,呼吸、轻微的头部运动)引起的体积渲染过程中的伪影。然而,该解决方案并未完全消除运动伪影,同时还使成像过程复杂化并导致患者不适。为了解决这个问题,我们报告了图像配准技术的实施,以正确对齐 B 模式 PA-US 图像并生成无伪影的 2D 横截面。当在步进电机扫描期间有意施加抖动时,将去抖动技术应用于 PA 模型显示与地面真实情况有 80% 的相似性。还可以使用 LED PA-US 扫描仪去除手持扫描的图像。在离体猪下颌骨,牙釉质的色素沉着被很好地估计在 0.1 毫米的误差范围内。在健康人类受试者身上测得的口袋深度也与我们之前的研究非常一致。该报告表明,独立于模态的配准技术可应用于牙周组织的临床相关 PA-US 扫描,以减少操作者的技能负担和受试者不适,同时显示手持式临床牙周成像的潜力。
更新日期:2021-03-01
down
wechat
bug