Fluid therapy is extensively used to treat traumatized patients as well as patients during surgery. The fluid therapy process is complex due to interpatient variability in response to therapy as well as other complicating factors such as comorbidities and general anesthesia. These complexities can result in under- or over-resuscitation. Given the complexity of the fluid management process as well as the increased capabilities in hemodynamic monitoring, closed-loop fluid management can reduce the workload of the overworked clinician while ensuring specific constraints on hemodynamic endpoints are met with higher accuracy. The goal of this paper is to provide an overview of closed-loop control systems for fluid management and highlight several key steps in transitioning such a technology from bench to the bedside.

流体疗法被广泛用于治疗受创伤的患者以及手术期间的患者。由于患者之间对治疗的反应以及其他复杂因素（例如合并症和全身麻醉）的不同，液体疗法的过程十分复杂。这些复杂性可能导致复苏不足或过度。考虑到流体管理过程的复杂性以及血液动力学监测功能的增强，闭环流体管理可以减少过度劳累的临床医生的工作量，同时确保以更高的准确性满足血液动力学终点的特定要求。本文的目的是概述用于流体管理的闭环控制系统，并重点介绍将这种技术从工作台过渡到床边的几个关键步骤。