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Dopaminergic and neurotrophic genetic polymorphisms modulate the implicit gender–science stereotype
PsyCh Journal ( IF 1.559 ) Pub Date : 2021-02-22 , DOI: 10.1002/pchj.428
Yu L. L. Luo 1, 2, 3 , Jie Chen 2, 3 , Yuqi Wang 4 , Xinying Li 2, 3 , Huajian Cai 1, 3
Affiliation  

Genetic approaches to both the gender–science stereotype and implicit social cognition have received increasing attention in recent years. We explored whether single nucleotide polymorphisms (SNPs) in dopaminergic and neurotrophic systems (i.e., COMT, BDNF genotypes) explain variations in the implicit gender–science stereotype. We genotyped 413 adolescents and assessed their implicit gender–science stereotype with the Implicit Association Test. Replication on a subsample (N = 312) was conducted 2 years later. Results showed that SNP-level variations within the COMT and BDNF genes were consistently associated with the implicit gender–science stereotype in both investigations. These findings suggest that variants in the COMT and BDNF genes may contribute to the variation of implicit gender–science stereotype.

中文翻译:

多巴胺能和神经营养遗传多态性调节内隐的性别科学刻板印象

近年来,性别科学刻板印象和内隐社会认知的遗传方法受到越来越多的关注。我们探讨了多巴胺能和神经营养系统(即 COMT、BDNF 基因型)中的单核苷酸多态性 (SNP) 是否可以解释隐含的性别科学刻板印象的变化。我们对 413 名青少年进行了基因分型,并通过内隐联想测试评估了他们内隐的性别科学刻板印象。2 年后对子样本 ( N = 312) 进行了复制。结果表明,在两项调查中,COMT 和 BDNF 基因内的 SNP 水平变异始终与隐含的性别科学刻板印象相关。这些发现表明 COMT 和 BDNF 基因的变异可能导致内隐性别科学刻板印象的变化。
更新日期:2021-02-22
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