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Pulmonary Artery Aneurysm in a Greater Flamingo (Phoenicopterus roseus) Associated with Aspergillus fumigatus Infection
Journal of Comparative Pathology ( IF 0.8 ) Pub Date : 2021-02-22 , DOI: 10.1016/j.jcpa.2021.01.006
Inês B Veiga 1 , Kerstin Hahn 1 , Christian Wenker 2 , Fabia Wyss 2 , Konrad Mühlethaler 3 , Horst Posthaus 1 , Jan Janzen 4
Affiliation  

We report necropsy findings in a captive 60-year-old female greater flamingo (Phoenicopterus roseus) that died suddenly following rupture of a pulmonary artery aneurysm. Histologically, there was focally extensive, intramural granulomatous inflammation with intralesional fungal hyphae, and adjacent severe mixed-cell inflammation and acute haemorrhage at the rupture site. Aspergillus fumigatus was identified as the aetiological agent following DNA PCR amplification and sequencing from paraffin-embedded pulmonary artery tissue sections. The most likely explanation is that this lesion was a consequence of haematogenous spread, secondary to mycotic pneumonia or aerosacculitis, following aspiration of A. fumigatus conidiospores. However, no further fungal-related lesions were observed on gross or histopathological examination.



中文翻译:

与烟曲霉感染相关的大火烈鸟(Phoenicopterus roseus)的肺动脉瘤

我们报告了一只圈养的 60 岁雌性大火烈鸟 ( Phoenicopterus roseus ) 的尸检结果,该火烈鸟在肺动脉瘤破裂后突然死亡。组织学上,有局灶性广泛的壁内肉芽肿性炎症,病灶内有真菌菌丝,破裂部位附近有严重的混合细胞炎症和急性出血。在对石蜡包埋的肺动脉组织切片进行 DNA PCR 扩增和测序后,烟曲霉被确定为病原体。最可能的解释是,这种病变是血液传播的结果,继发于真菌性肺炎或气管炎,继发于A熏烟分生孢子。然而,在肉眼或组织病理学检查中没有观察到进一步的真菌相关病变。

更新日期:2021-02-23
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