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Are hospitalized patients with inflammatory bowel disease at increased risk of invasive bacterial infections? Results from POLIBD 3-year cohort study
Gut Pathogens ( IF 4.2 ) Pub Date : 2021-02-22 , DOI: 10.1186/s13099-021-00408-6
Jolanta Gruszecka , Rafał Filip

The aim of this study was to determine the dominant species of bacteria found in blood cultures collected from patients under treatment in the tertiary inflammatory bowel disease (IBD) center in Poland. The dominant pathogen isolated from blood in patients with IBD was Staphylococcus epidermidis MRCNS (MRCNS—methicillin-resistant coagulase-negative Staphylococcus), a strain resistant to all beta-lactam antibiotics (penicillins, penicillins with B-lactamase inhibitor, cephalosporins and carbapenems). The second most commonly isolated pathogen found in the blood samples was Escherichia coli. Blood cultures were found to be positive for these pathogens more frequently in male patients (90.0%). An increased risk of bacteremia in IBD patients was associated with prolonged hospitalization.

中文翻译:

住院的炎症性肠病患者是否具有增加的侵入性细菌感染风险?POLIBD 3年队列研究的结果

这项研究的目的是确定在波兰第三级炎症性肠病(IBD)中心接受治疗的患者的血液培养物中发现的主要细菌种。在IBD患者中,从血液中分离出的主要病原体是表皮葡萄球菌MRCNS(MRCNS,耐甲氧西林凝固酶阴性葡萄球菌),该菌株对所有β-内酰胺抗生素(青霉素,带有B-内酰胺酶抑制剂的青霉素,头孢菌素和碳青霉烯类抗生素)都有抵抗力。在血液样本中发现的第二种最常见的病原体是大肠杆菌。在男性患者中,血液培养对这些病原体呈阳性的频率更高(90.0%)。IBD患者发生菌血症的风险增加与住院时间延长有关。
更新日期:2021-02-22
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