Abstract

Context

Proper nutrition and exercise are effective strategies to improve overall metabolic health in diabetic patients.

Objective

This study evaluated the effects of Nigella sativa (NS) supplementation during resistance training (RT) on some biochemical variables in type 2 diabetes patients.

Methods

Forty patients were assigned to groups: RT + NS (RN), NS, RT + placebo (RP), and control (CO). RT was performed and NS was consumed for 8 weeks. Blood samples were collected at rest immediately before and after the 8 week intervention.

Results

RT or NS by themselves reduced HOMA-IR, insulin, glucose, TG, TC, LDL, ESR, CRP, AST, ALT and ALP, and increased HDL and HOMA-S. The combination of RT and NS, rather than each intervention alone, had significant effects on reduction of HOMA-IR, insulin, ESR and CRP as well as increases in HDL, HOMA-β/S.

Conclusion

RT combined with NS is sometimes a better strategy compared to single interventions for improving diabetes related biomarkers in type 2 diabetic patients.

中文翻译：

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阻力训练和黑种草对 2 型糖尿病的影响：对代谢标志物、低度炎症和肝酶产生的影响

摘要

语境

适当的营养和运动是改善糖尿病患者整体代谢健康的有效策略。

客观的

本研究评估了阻力训练 (RT) 期间补充黑种草 (NS) 对 2 型糖尿病患者某些生化指标的影响。

方法

40 名患者被分配到以下组：RT + NS (RN)、NS、RT + 安慰剂 (RP) 和对照组 (CO)。进行 RT 并服用 NS 8 周。在 8 周干预前后立即采集静息时的血样。

结果

RT 或 NS 本身可降低 HOMA-IR、胰岛素、葡萄糖、TG、TC、LDL、ESR、CRP、AST、ALT 和 ALP，并增加 HDL 和 HOMA-S。RT 和 NS 的组合，而不是单独的每种干预，对 HOMA-IR、胰岛素、ESR 和 CRP 的降低以及 HDL、HOMA-β/S 的增加具有显着效果。

结论

与单一干预措施相比，RT 联合 NS 有时是改善 2 型糖尿病患者糖尿病相关生物标志物的更好策略。