There is paucity of human data about the effects of depot medroxyprogesterone (DMPA) and norethisterone enanthate (Net-En) use on systemic immune function, which may have implications for reproductive tract infection susceptibility and transmissibility. We sought to evaluate the impact of injectable contraceptive use on T-cell responsiveness using T cells exposed in vivo and tested ex vivo.

中文翻译：

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仅注射孕激素避孕药、长效醋酸甲羟孕酮和庚酸炔诺酮对 T 细胞活化过程中细胞因子产生的影响

缺乏关于长效甲羟孕酮 (DMPA) 和庚酸炔诺酮 (Net-En) 使用对全身免疫功能影响的人类数据，这可能对生殖道感染的易感性和传播性有影响。我们试图使用体内暴露和体外测试的 T 细胞评估注射避孕药对 T 细胞反应性的影响。