The South American soybean pest, Rachiplusia nu (Guenée), is naturally infected by Autographa californica multiple nucleopolyhedrovirus (AcMNPV) and Rachiplusia nu nucleopolyhedrovirus (RanuNPV). We compared their pathogenicity to fourth-instar R. nu larvae, by evaluating time to death and virus spread throughout the tissues in single and mixed infections. Bioassays showed that generalist AcMNPV had a faster speed of kill than specific RanuNPV, while the mixed-virus treatment did not statistically differ from AcMNPV alone. Histopathology evidenced similar tissue tropism for both viruses, but co-inoculation resulted in mostly AcMNPV-infected cells. In sequential inoculations, however, the first virus administered predominated over the second one. Implications on baculovirus interactions and biocontrol potential are discussed.

中文翻译：

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单次和混合接种后Rachiplusia nu（鳞翅目：夜蛾科）幼虫中通才AcMNPV和特异性RanuNPV的比较发病机制

南美大豆害虫 Rachiplusia nu (Guenée) 会自然感染 Autographa californica 多核多角体病毒 (AcMNPV) 和 Rachiplusia nu 核多角体病毒 (RanuNPV)。我们通过评估单一感染和混合感染中的死亡时间和病毒在整个组织中的传播，将它们与四龄 R. nu 幼虫的致病性进行了比较。生物测定表明，通才 AcMNPV 的杀灭速度比特定的 RanuNPV 更快，而混合病毒治疗与单独的 AcMNPV 没有统计学差异。组织病理学证明这两种病毒具有相似的组织嗜性，但共同接种导致大部分受 AcMNPV 感染的细胞。然而，在连续接种中，施用的第一种病毒优于第二种病毒。讨论了对杆状病毒相互作用和生物防治潜力的影响。