Highly toxic iodinated phenolic by-products were frequently detected in the oxidative treatment and disinfection of iodine-containing water. Herein, it was found that three model iodinated phenolic disinfection byproducts (DBPs), 2-iodophenol, 4-iodophenol and 2,4,6-triiodophenol, were reactive with HOCl, and the reaction rate constants (at pH 7.0 and 25℃) were 1.86 ×10², 1.62 ×10² and 7.5 ×10¹ M⁻¹s⁻¹, respectively. When HOCl was in excess (HOCl/iodophenol = 40/1, [iodophenol]₀ = 20 μM), acute toxicity of water sample containing iodophenols could be largely eliminated (> 85%), with the conversion of iodophenols into stable and non-toxic iodate (IO₃⁻) and iodinated and chlorinated aliphatic DBPs. Besides IO₃⁻, seven kinds of aromatic intermediate products including iodophenols, chloroiodophenols, iodoquinones, chloroiodoquinones, chloroquinones, chlorophenols, and coupling products were detected. C-I bond of iodophenols was cleaved in the reaction and the resulted aromatic products were further transformed into chlorinated aliphatic DBPs [trichloromethane (TCM), trichloroacetic acid (TCAA), dichloroacetic acid (DCAA), and chloral hydrate (CH)] (mg/L level) and iodinated trihalomethanes (μg/L level). HOCl was effective for converting iodophenols into IO₃⁻ and less toxic chlorinated aliphatic DBPs. Considering that chlorine was widely used as disinfectant, transformation and toxicity alteration of emerging DBPs during chlorination/booster chlorination warrant further investigations.

在含碘水的氧化处理和消毒中经常检测到剧毒的碘化酚类副产物。在此发现，三种模型碘化酚醛消毒副产物（2-碘苯酚，4-碘苯酚和2,4,6-三碘苯酚）可与HOCl反应，且反应速率常数（在pH 7.0和25℃下）分别为1.86×10 ²，1.62×10 ²至7.5×10 ¹中号^-1小号^-1，分别。当HOCl过量时（HOCl /碘苯酚= 40/1，[碘苯酚] ₀  = 20μM），含有碘苯酚的水样品的急性毒性可以大大消除（> 85％），并将碘苯酚转化为稳定的和非碘的。有毒的碘酸盐（IO ₃ ^-）以及碘化和氯化的脂肪族DBP。除了IO ₃ ^- ，检测到7种芳香族中间产品，包括iodophenols，chloroiodophenols，iodoquinones，chloroiodoquinones，chloroquinones，氯酚，和偶联产物。碘酚的CI键在反应中裂解，所得芳族产物进一步转化为氯化脂肪族DBP [三氯甲烷（TCM），三氯乙酸（TCAA），二氯乙酸（DCAA）和水合氯醛（CH）]（mg / L含量）和碘代三卤甲烷（μg/ L含量）。次氯酸是有效的转化成iodophenols IO ₃ ^-和毒性较小的氯化脂肪族DBP。考虑到氯已被广泛用作消毒剂，因此在加氯/加强氯化过程中，新出现的DBP的转化和毒性改变值得进一步研究。