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Ring opening reactions of nitrogen heterocycles
Russian Chemical Reviews ( IF 7.7 ) Pub Date : 2019-10-31 , DOI: 10.1070/rcr4891
A V Smolobochkin , A S Gazizov , A R Burilov , M A Pudovik , O G Sinyashin

Published data on ring opening reactions of nitrogen-containing cyclic compounds resulting in various acyclic products are integrated and systematized. The reactions of common five-, six- and seven-membered nitrogen heterocycles containing one to four nitrogen atoms in the ring and having various structures (mononuclear, polynuclear, fused, saturated, unsaturated and aromatic) are considered. Special emphasis is made on the potential of nitrogen heterocycles for the synthesis of polyfunctional open-chain compounds. The advantages and disadvantages of the proposed approaches are noted. Data on the biological activities of some ring opening products of the title heterocycles are presented. The text is arranged according to the type of reagents and catalysts used.

The bibliography includes 196 references.



中文翻译:

氮杂环的开环反应

已发表的关于含氮环状化合物开环反应产生各种无环产物的数据被整合和系统化。考虑了在环中含有一到四个氮原子并具有各种结构(单核、多核、稠合、饱和、不饱和和芳族)的常见五元、六元和七元氮杂环的反应。特别强调了氮杂环在合成多功能开链化合物方面的潜力。指出了所提出方法的优点和缺点。提供了标题杂环的一些开环产物的生物活性数据。正文根据所用试剂和催化剂的类型排列。

参考书目包括 196 篇参考文献。

更新日期:2019-10-31
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