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Features, Pharmacological Chemistry, Molecular Mechanism and Health Benefits of Lemon
Medicinal Chemistry ( IF 2.3 ) Pub Date : 2021-02-28 , DOI: 10.2174/1573406416666200909104050
Nitika Singh 1 , Nagendra Sastry Yarla 2 , Nikhat Jamal Siddiqi 3 , Maria de Lourdes Pereira 4 , Bechan Sharma 1
Affiliation  

Background: Citrus limon, a Mediterranean-grown citrus species of plants belonging to the Rutaceae family, occupies a place of an impressive range of food and medicinal uses with considerable value in the economy of the fruit of the country. Citrus fruits are economically important with large-scale production of both the fresh fruits and industrially processed products. The extracts and phytochemicals obtained from all parts of C. limon have shown immense therapeutic potential because of their anticancer, anti-tumor and anti-inflammatory nature, and also serve as an important ingredient in the formulation of several ethnic herbal medicines. These properties are mediated by the presence of different phytochemicals, vitamins and nutrients in the citrus fruits.

Material and Methods: The methods involved in the preparation of the present article included the collection of information from various scientific databases, indexed periodicals, and search engines such as Medline Scopus google scholar PubMed, PubMed central web of science, and science direct.

Results: This communication presents an updated account of different pharmacological aspects of C. limon associated with its anti-oxidative, antiulcer, antihelmintic, insecticidal, anticancer, cytotoxic, and estrogenic activities. In addition, C. limon extracts possess hepatoprotective, anti-hyperglycemic, and antimicrobial properties. The present article includes the structure and function of different key chemical constituents from different parts of C. limon. Also, the possible molecular mechanisms of actions of bioactive compounds from C. limon are displayed.

Conclusion: The traditional and ethno-medicinal literature revealed that C. limon is very effective in different pathologies. Most of these compounds possessing antioxidant properties would be implicated in offering health benefits by acting as potential nutraceuticals to humans with special reference to disease management of health and disease.



中文翻译:

柠檬的特性,药理化学,分子机理和健康益处

背景:柑桔属柠檬科植物,属于芸香科,是地中海种植的柑橘类植物,在食品和药物用途方面占据着举足轻重的地位,对该国的水果经济具有重要价值。柑橘类水果对新鲜水果和工业加工产品的大规模生产在经济上都很重要。从柠檬衣藻的各个部位获得的提取物和植物化学物质具有抗癌,抗肿瘤和抗炎的性质,因此具有巨大的治疗潜力,并且在几种民族草药的配制中也起着重要的作用。这些特性是由柑橘类水果中存在的不同植物化学物质,维生素和营养物质介导的。

资料和方法:编写本文所涉及的方法包括从各种科学数据库,索引期刊和搜索引擎(如Medline Scopus谷歌学者PubMed,PubMed中央科学网络和直接科学)收集信息。

结果:本通讯介绍了柠檬柠檬假单胞菌与其抗氧化,抗溃疡,抗蠕虫,杀虫,抗癌,细胞毒性和雌激素活性有关的不同药理学方面的最新情况。此外,柠檬柠檬衣藻提取物还具有保肝,抗高血糖和抗微生物的特性。本文包括柠檬柠檬梭菌不同部位不同关键化学成分的结构和功能。而且,显示了柠檬柠檬梭菌生物活性化合物作用的可能分子机理。

结论:传统和民族医学文献表明,柠檬衣原体在不同的病理学上都非常有效。这些具有抗氧化特性的化合物中的大多数都将通过作为人类潜在的营养保健品(特别涉及健康和疾病的疾病管理)而提供健康益处。

更新日期:2021-02-18
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