In this letter, we present a compact and low cost smartphone based oblique incidence reflectometer (OIR) for the measurement of tissue optical properties in vitro. The proposed lightweight OIR system obliquely delivers a narrow laser light by the attached inexpensive laser diode onto the surface of the matter under test. The incident laser light produces a spatial distribution of diffuse reflectance which is not centered at the point of incidence. The built-in CMOS image sensor in the smartphone samples the relative profile of diffuse reflectance. The profile is rapidly and efficiently processed through a custom-developed smart application running on the phone for calculating the absorption coefficient and the reduced scattering coefficient. Phantom experiments have demonstrated the proposed OIR can achieve a measurement error less than 5% benchmarked with the bulky and expensive laboratory setup. Measurement results can either be stored locally for real-time application or sent to cloud, providing remote diagnosis opportunities even in the field settings.

在这封信中，我们介绍了一种紧凑且低成本的基于智能手机的斜入射反射仪（OIR），用于体外测量组织的光学特性。所提出的轻型OIR系统通过连接的廉价激光二极管将窄激光束倾斜地发射到被测物质的表面上。入射激光产生漫反射率的空间分布，该空间分布不以入射点为中心。智能手机中的内置CMOS图像传感器对漫反射率的相对轮廓进行采样。通过在电话上运行的定制开发的智能应用程序可以快速有效地处理此配置文件，以计算吸收系数和降低的散射系数。幻影实验已经证明，在庞大而昂贵的实验室设置中，建议的OIR可以实现小于5％的测量误差。测量结果既可以存储在本地以供实时应用，也可以发送到云中，